Weight Loss
Simplified.

Provider-reviewed treatment options delivered directly to your door

Your plan. Simplified.

Choose your treatment to view plans and pricing. Your provider will review your intake and may request a video appointment prior to issuing a prescription at their discretion.

Your treatment. Explained.

Explore how each medication works, what to expect, and the safety information to discuss with your provider.

Compounded treatment option

Semaglutide

A prescription medicine that acts on GLP-1 receptors involved in appetite and food intake. Somira offers a compounded injectable option for provider-reviewed weight-management care. [2] [1]

  • GLP-1 receptor agonist
  • Once-weekly injection, as prescribed
  • Options with B12 or glycine

Your provider determines eligibility, formulation and dose. Review the compounding notice and safety information below.

Planning a pregnancy?

For weight management, semaglutide should be stopped at least 2 months before a planned pregnancy. Discuss the timing with your prescriber. [2]

View semaglutide plans →

How it works & potential benefits

Semaglutide acts like the GLP-1 hormone. It can reduce hunger, increase fullness, slow stomach emptying, and help regulate blood sugar. Lower calorie intake may support weight management alongside nutrition and physical activity. [2]

Potential changes include less frequent cravings and improved portion control. Your response and weight-loss results will vary; no result or timeline is guaranteed. [1]

What to expect & practical tips

Your provider determines eligibility and a starting dose, then may adjust it gradually according to your response and tolerability. Do not increase it on your own. Weight change is gradual, and follow-up is part of treatment. [1]

For mild nausea or stomach upset, smaller meals, slow eating, adequate fluids, and avoiding large or high-fat meals may help. Ask your care team about symptoms that persist or limit eating and drinking. [7]

Common side effects

Examples reported with FDA-approved Semaglutide injections include:

  • Nausea or vomiting
  • Diarrhea or constipation
  • Abdominal discomfort
  • Hair loss
  • Skin sensitivity or unusual skin sensations
  • Bloating, gas or belching
  • Indigestion or heartburn
  • Headache or dizziness
  • Fatigue

This is not a complete list, and compounded formulations may differ. Contact your provider for persistent or worsening symptoms. A serious allergic reaction needs emergency care. [6]

Important safety & medicine interactions
  • Do not use with a personal or family history of medullary thyroid carcinoma (MTC), MEN 2, or a previous serious allergy to semaglutide or an ingredient.
  • Stomach and other conditions: Severe digestive problems, pancreatitis, gallbladder disease and dehydration-related kidney injury can occur. Use is not recommended with severe gastroparesis (very slow stomach emptying).
  • Diabetes and heart rate: Discuss low-blood-sugar risk, especially with insulin or sulfonylureas. Report vision changes and a racing heartbeat at rest.
  • Medicine review: Tell your provider about all medicines and supplements. Slower stomach emptying can affect oral medicines. Do not combine with another semaglutide product or GLP-1 medicine.

This is not a complete list of risks or interactions. Your prescriber must review your medical history, including pancreas, gallbladder, kidney and diabetic eye problems. [6] [2]

Pregnancy, breastfeeding & procedures

Pregnancy: Do not use for weight loss during pregnancy. Stop treatment and contact your prescriber if you become pregnant; arrange to stop at least 2 months before trying to conceive. [2]

Breastfeeding: Discuss treatment with your prescriber before use, including potential risks and benefits for you and your child. [2]

Procedures: Tell the anesthesia team before surgery or deep sedation. Delayed stomach emptying can increase aspiration risk. Let that team decide any changes to your medication and fasting plan. [6]

Important thyroid warning

FDA-approved semaglutide and tirzepatide products carry a boxed warning about thyroid C-cell tumors. Tumors occurred in rodent studies; whether these medicines cause them in people is unknown.

Do not use if you or a family member has had medullary thyroid carcinoma (MTC), or you have multiple endocrine neoplasia syndrome type 2 (MEN 2). Report a neck lump, persistent hoarseness or trouble swallowing. [2] [3]

Know when to get help

Call 911 for trouble breathing, facial or throat swelling, collapse, or other signs of a severe allergic reaction.

Stop the medicine and seek urgent care for severe, persistent abdominal pain, especially if it reaches your back, with or without vomiting.

Promptly contact a clinician for ongoing vomiting or diarrhea, inability to keep fluids down, very little urine, jaundice or vision changes. Do not wait for a portal reply in an emergency. [6] [3]

About compounded medications. These products are not FDA-approved. FDA does not review their safety, effectiveness or quality before marketing, and they are not FDA-approved generic versions of Wegovy, Ozempic, Zepbound or Mounjaro. FDA recommends compounding only when a patient’s medical needs cannot be met by an approved drug.

The branded-product safety sources here do not establish the safety or effectiveness of a compounded formulation. Read Somira’s compounding notice.

Sources & full medication information

Source check: September 17, 2026. The prescribing-information sources below describe FDA-approved branded products, not approval of compounded preparations. Product-specific instructions must come from your prescriber and dispensing pharmacist.

  1. Somira weight-loss treatment information (new tab)
  2. Wegovy: official semaglutide labeling (DailyMed) (new tab)
  3. Zepbound: official tirzepatide labeling (DailyMed) (new tab)
  4. FDA: concerns with unapproved GLP-1 medicines (new tab)
  5. FDA: compounded semaglutide dosing errors (new tab)
  6. Wegovy: patient safety information (new tab)
  7. Zepbound: side effects and patient safety information (new tab)
B12, glycine & your formulation

Somira lists B12 and glycine formulations for both medications. Your provider and pharmacist should confirm which ingredients, concentration and formulation are appropriate. Tell them about all allergies. [1]

Do not assume an added ingredient makes a compounded medicine equivalent to an approved medicine, improves weight loss or prevents side effects. FDA notes that the safety and effectiveness of combining semaglutide with additional ingredients, including B12, have not been established. [5]

Dosing, storage & safe use
  • Confirm the dose before injecting. Ask your pharmacist to show the prescribed amount in milligrams, the corresponding volume, and the correct syringe marking. Do not copy “units” from a different vial or concentration.
  • Follow your prescription. Do not increase the dose, inject more frequently, or restart after a treatment gap without instructions. Contact your care team for missed-dose guidance.
  • Storage and delivery: Follow the pharmacy’s storage instructions. Do not use a compounded GLP-1 injection that arrives damaged or cloudy; contact the dispensing pharmacy.
  • Opened multidose vials: FDA advises discarding within 28 days after first use, even if medicine remains or the compounder gives a longer period. Follow an earlier beyond-use date when applicable; clarify any conflicting directions with the pharmacy.
  • Injection supplies: Use a new sterile needle and syringe each time and do not share supplies or medication.

Ask for help whenever the label, vial concentration or syringe markings are unclear. This widget intentionally does not provide injection-unit conversions. [5] [4]

Educational information, not a diagnosis or personalized treatment advice. Prescription and provider approval required. This summary does not include every risk, interaction or instruction and does not replace the counseling provided with your prescription.

Why Choose Somira Health
   for Medical Weight Loss?

Transparent

Built Around You

Too many companies rely on memberships, hidden fees, changing prices, and fine print that makes it difficult to know what you’re actually paying for.

Provide provider-guided medical weight loss with transparent pricing, no hidden fees, and a patient experience designed around clarity and trust.

From your first provider reviewed intake to your Semaglutide or Tirzepatide delivery by one of our U.S. based licensed 503a pharmacy partners, every step is intended to be straightforward—so you can focus on your health instead of navigating complicated healthcare.

Somira was founded on the belief that patients deserve the same transparency and respect from healthcare that they expect from every other important service in their lives.

Real Patients. Real Reviews.