Women’s Health
Simplified.
Provider-reviewed treatment options delivered directly to your door
Women’s Health Plans
Your care. Simplified.
Choose your treatment to view plans and pricing. Your provider will review your intake and set up a video appointment prior to issuing a prescription.
IMPORTANT INFORMATION for Hormone Treatment.
The following are required prior to treatment approval:
- Video telehealth appointment is required to discuss treatment options
- Recent bloodwork labs are required (within the last 90 days)
- Follow up labs are required at least every 6 months
- Bloodwork labs may be uploaded or purchased from the portal
Ordering Labs
You will be given the option to upload your recent bloodwork through the portal.
If you do not have recent bloodwork labs, you can order them through our portal.
- Initial lab cost is $75
- Follow up lab cost is $51
What’s included
Once purchased, you will be given a nearby location for a collection facility to complete your bloodwork. Your provider will review your results with you.
Your initial labs include the following markers:
- CBC Panel
- Metabolic Panel
- Lipid Panel
- FSH
- Progesterone
- Estradiol
- TSH
- SHBG
- DHEA
- Total Testosterone
- LH
- Cortisol A.M.
Follow up purchased labs will include the following markers:
- DHEA
- FSH
- Estradiol
- Progesterone
- LH
- Total Testosterone
NOTE: Lab work is non-refundable even if your provider denies treatment.
Know your treatment
Your treatment. Explained.
Explore your hormone-care options, what to expect, and the safety information to discuss with your provider.
Estrogen therapy
Estradiol
Estradiol replaces an estrogen hormone that declines around menopause. Somira lists topical treatment options; the appropriate formulation depends on your symptoms and medical history. [1] [11]
- Topical treatment options
- Symptom-focused care
- Provider-selected formulation
Your provider confirms eligibility, formulation and dose. The reference labels describe approved products, not approval of a compounded preparation.
Do you still have a uterus?
With systemic estrogen, an appropriate progestogen is usually needed to protect the uterine lining. Ask your provider before choosing estrogen alone. [6]
How it works & potential benefits
Systemic estradiol reaches the bloodstream and can help reduce hot flashes and night sweats. Local, low-dose vaginal estrogen has a different role. Relief, risks and treatment goals depend on the route and dose. [2] [7]
What to expect & follow-up
Improvement may be gradual. Track symptoms and side effects so your provider can review the response and adjust treatment when appropriate. Do not increase the amount yourself. A specific improvement or timeline is not guaranteed. [10]
Common side effects
Possible effects include:
- Breast tenderness
- Headache
- Nausea or bloating
- Skin irritation where applied
- Spotting or bleeding changes
- Mood changes
Report unexpected bleeding, including bleeding after menopause, rather than assuming it is harmless. Persistent or worsening effects need provider review; this list is not complete. [3]
Important safety & interactions
Systemic estrogen should not be used with unexplained genital bleeding, current or past breast cancer, estrogen-dependent cancer, a history of blood clots, stroke or heart attack, certain clotting disorders, liver disease, or an allergy to its ingredients. [2]
Review all medicines and supplements, including thyroid treatment. Also discuss migraines, gallbladder problems, high triglycerides and upcoming surgery or prolonged immobility. Your individual risk review cannot be replaced by this summary. [2]
Skin application vs. vaginal estrogen
These are not interchangeable. Low-dose vaginal estrogen treats local dryness and irritation and generally does not require added progesterone; it does not treat hot flashes. That distinction does not mean every estrogen cream is a low-dose vaginal product. [7]
Use your medicine only by the prescribed route. With a skin-applied product, follow pharmacy instructions to prevent transfer to children, partners or pets, including handwashing and appropriate covering of the treated skin. [3]
Progesterone therapy
Progesterone
Progesterone can help prevent excessive thickening of the uterine lining when used with estrogen in someone who has a uterus. Somira lists an oral treatment option. [5] [1]
- Oral treatment options
- May accompany systemic estrogen
- Schedule tailored by your provider
Your provider confirms eligibility, formulation and dose. The reference labels describe approved products, not approval of a compounded preparation.
Drowsiness & ingredient allergies
Oral progesterone may cause drowsiness or dizziness. Do not drive when affected. Some products contain peanut oil; ask the dispensing pharmacy to check your exact ingredients and allergies. [5]
Why it may be prescribed
In menopausal hormone therapy, progesterone counters estrogen’s stimulation of the uterine lining. It may also be prescribed for certain cases of absent periods after evaluation. The reason for prescribing it should be clear in your care plan. [4]
Your schedule & what to expect
Your prescription may use a continuous or a cyclic schedule. Confirm which days to take it and whether bedtime dosing is intended. Do not copy another patient’s regimen or stop it on your own just because you feel better. [10] [4]
Common side effects
Possible effects include:
- Drowsiness or dizziness
- Headache
- Breast tenderness
- Stomach discomfort
- Fatigue
- Mood changes
Bleeding or discharge changes can also occur. Report unexpected bleeding and any persistent or severe symptoms. Effects differ by product and treatment plan. [4]
Important safety & interactions
Oral micronized progesterone labeling excludes use with unexplained vaginal bleeding, certain cancers including a breast-cancer history, current or past blood clots, stroke or heart attack, liver disease, or an ingredient allergy. Your prescriber must check your exact product. [5]
Provide a complete medicine and supplement list, including St. John’s wort. Discuss mood symptoms and any medicine that makes you sleepy. Follow product-specific food and timing instructions rather than assuming all oral products are the same. [4]
What progesterone does not replace
Progesterone does not replace an evaluation for unexplained bleeding or new symptoms. Symptoms such as poor sleep, fatigue and mood changes can have more than one cause; your provider will decide whether hormonal or other care is appropriate. [1]
This menopause-care guide does not provide a fertility or pregnancy-support regimen. Those uses require separate prescribing instructions.
Coordinated hormone care
Estradiol + Progesterone
Somira’s bundle brings topical estradiol and progesterone into one provider-reviewed treatment plan. It is a care-plan combination, not a statement that the medicines are mixed into one product. [1]
- Two hormones with different roles
- Individualized directions for each
- Follow-up and safety review
Your provider confirms eligibility, formulation and dose. The reference labels describe approved products, not approval of a compounded preparation.
When progesterone is prescribed for uterine protection, do not drop it while continuing systemic estrogen without speaking with your prescriber. [6]
The prescribed combination matters
Why these treatments may be combined
Estrogen can relieve menopausal symptoms. For someone who has a uterus, an appropriate progestogen helps reduce the risk of estrogen-related overgrowth of its lining. Taking both is not automatically the best choice for everyone. [8]
Coordinating your treatment
Ask for clear written directions for each medicine, including dose, route and days of use. Your prescriber should review changes in symptoms, bleeding patterns and side effects and decide whether to continue or adjust care. [10]
The bundle does not establish a universal dose or schedule; follow the prescriptions issued for you.
Common side effects
Possible effects include:
- Breast tenderness
- Headache
- Nausea or bloating
- Drowsiness or dizziness
- Skin irritation from topical use
- Spotting or bleeding changes
Either medicine can contribute to side effects. Read both individual guides, report unexpected bleeding, and contact your provider for persistent or worsening symptoms. [1] [5]
Important safety for combined treatment
Combined hormone therapy still has risks, including blood clots, stroke and certain cancers. Adding progesterone does not make estrogen risk-free. Your medical history, age, timing, formulation and duration all matter. [11] [6]
Review the contraindications for both medicines above, disclose all allergies and other treatments, and keep recommended follow-up and screening appointments. [11]
Does everyone need both medicines?
Not necessarily. People without a uterus generally do not need progesterone for uterine protection, though there can be other reasons to prescribe it. Low-dose local vaginal estrogen is also different from systemic estrogen. [6] [7]
Your provider should decide whether the bundle, a single treatment or a nonhormonal option fits your needs. Do not add or remove a hormone solely to match a pricing option.
Important estrogen & uterine safety
Systemic estrogen without adequate progestogen can increase the risk of cancer of the uterine lining in someone who has a uterus. An appropriate progestogen regimen helps reduce estrogen-related lining overgrowth; it does not remove every hormone-therapy risk. [2]
Report unexplained vaginal bleeding, especially after menopause. Do not assume a hormone change explains it. Your provider may need to investigate. [8]
Know when to get help
Call 911 for chest pain, sudden breathing difficulty, facial or throat swelling, or possible stroke symptoms such as sudden weakness, speech trouble or vision loss. [4]
Seek urgent assessment for new one-sided leg pain or swelling. Promptly report unusual bleeding, a new breast lump, or yellowing of the skin or eyes. Do not wait for a portal reply in an emergency. [3]
About compounded hormones. A compounded medication is not FDA-approved and is not reviewed by FDA for safety, effectiveness or quality before marketing. References to approved estradiol or progesterone products do not establish approval or equivalent performance of a compounded preparation. [9]
“Bioidentical” does not mean a compounded product is proven safer or more effective. Confirm the exact prescribed product with your provider and pharmacist. [8]
Pregnancy, breastfeeding & contraception
Menopausal hormone therapy is not birth control. Discuss contraception if pregnancy is possible. Tell your prescriber before treatment if you are pregnant, trying to conceive or breastfeeding, and contact them promptly if pregnancy occurs. [10] [11]
Estrogen treatment for menopause is not intended for pregnancy. Do not use this guide to start, stop or alter progesterone prescribed for fertility or pregnancy support; ask that prescribing team for instructions. [8]
Using and storing your prescription
Follow the pharmacy’s exact dose, route, schedule and storage instructions. Do not substitute pump counts, cream amounts, capsule strengths or another person’s directions. Ask your pharmacist about a missed dose rather than doubling it. [3] [4]
Keep medicines out of reach of children, do not share them, and follow the pharmacy’s expiry or beyond-use date. Tell your surgical team about hormone therapy before a procedure; any temporary changes must be planned with your clinician. [3] [4]
Treatment goals & ongoing review
Hormone therapy is a treatment decision, not a general anti-aging or weight-loss program. It should not be started to prevent heart disease, stroke or dementia. Discuss symptom goals, alternatives and your personal benefits and risks. [8]
Continue recommended checkups and screenings. Revisit the treatment when your symptoms, health history or preferences change. No single regimen is right for everyone. [11]
Sources & full medication information
Source check: September 17, 2026. The approved-product references below are educational references, not the label for every medicine dispensed through Somira. Your prescriber and pharmacist must supply the instructions and safety information for your exact prescription.
- Somira: Women’s Health treatments (new tab)
- FDA: Divigel (estradiol gel) prescribing information, revised February 2026 (PDF) (new tab)
- MedlinePlus: topical estradiol (new tab)
- MedlinePlus: progesterone (new tab)
- DailyMed: Prometrium (oral micronized progesterone) labeling, updated July 2026 (new tab)
- The Menopause Society: hormone therapy (new tab)
- NHS: low-dose vaginal estrogen (new tab)
- FDA: menopause and hormone treatment (new tab)
- FDA: understanding the risks of compounded drugs (new tab)
- NHS: hormone replacement therapy overview (new tab)
- MedlinePlus: hormone therapy for menopause (new tab)
Educational information, not a diagnosis or personalized treatment advice. Prescription and provider approval required. This summary does not include every risk, interaction or instruction and does not replace the counseling provided with your prescription.
Women’s Healthcare Should Feel Different
Simple
Transparent
Built Around You
Every woman experiences hormonal changes differently. Your care should reflect that.
At Somira Health, we believe women’s healthcare should be transparent, accessible, and centered around your individual needs. Your secure online intake is carefully reviewed by a licensed medical provider who determines whether treatment is clinically appropriate. If approved your medication is prepared for you by one of our U.S. based licensed 503a pharmacy partners.
Once you’re established as a patient, you’ll have continued access to your care team through our secure patient portal for ongoing support and follow-up.
Because great healthcare starts with trust.
Whether you’re navigating perimenopause, menopause, or other hormonal changes, our goal is to make accessing care simpler, more transparent, and easier to fit into your life.
Real Patients. Real Reviews.
“Me and my boyfriend started with Somira a few months ago. I was always leary of online health businesses as so many out there are crooks. However this company is who they claim they are. Quality service and products! We feel we made the best choice for our needs and continue to work with the doctors for our health goals.”
I placed my order and received my medications the next day! Had some questions that first week, contacted them and they always got to me fairly quickly whether it was the owner or provider! Which i appreciated bc they last company i used took a couple of days to respond. Highly recommend them!”