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Explore your options, what to expect, and the safety information to discuss with your provider.

Prescription ED treatment

Sildenafil

A tablet used for erectile dysfunction (ED). It helps blood reach the penis during sexual arousal; it does not create an automatic erection. [1]

  • PDE5 inhibitor
  • Taken as needed, as prescribed
  • Sexual stimulation is required

Your prescriber confirms the diagnosis, medicine and instructions. Read the safety notices below before starting treatment.

Before your first dose

Ask your provider to review your heart health and every medicine you use, including occasional chest-pain medicine and recreational “poppers.” [3]

View sildenafil plans →

How it works & why it is prescribed

Sildenafil supports the blood-flow response to stimulation by blocking PDE5. It can help with erections but does not increase sexual desire, cure ED, or protect against pregnancy or sexually transmitted infections. [3]

What to expect & practical use

It is often used about an hour before sex; a high-fat meal can delay its effect. Follow your own prescription’s timing and dose rather than taking extra tablets when it seems slow to work. [3]

Tell your care team when treatment is ineffective or poorly tolerated. Do not add tadalafil or other ED medicines on your own. [2]

Common side effects
  • Headache or flushing
  • Indigestion or nausea
  • Stuffy nose
  • Dizziness
  • Temporary blue-tinted vision
  • Back or muscle discomfort

Examples, not a complete list. Report persistent or worsening symptoms; see the urgent-care guidance below. [2]

Safety & medicine interactions

Do not use with nitrates, riociguat, or a known allergy to sildenafil or its ingredients. ED medicines are unsuitable when your cardiac condition makes sexual activity unsafe. [2]

Alpha-blockers, blood-pressure drugs and medicines such as ritonavir or certain antifungals may require changes to treatment. Discuss kidney/liver disease, previous serious vision loss, or a history of prolonged erections. [2]

Nitrates + ED medicine: do not combine

Nitroglycerin, isosorbide and nitrite “poppers” can cause a dangerous blood-pressure drop with sildenafil.

For chest pain, stop sexual activity, call 911 and tell responders when you last took it. Do not self-treat with a nitrate. [2] [3]

Get urgent medical help

An erection lasting more than 4 hours needs emergency care, even if painless.

Stop ED medicine and seek immediate care for sudden vision or hearing loss. Call 911 for breathing difficulty, throat swelling or collapse. [2] [3]

Know which product you receive. These references describe FDA-approved products and clinical guidance; they do not identify the exact brand or formulation dispensed to you. If a medication is compounded, it is not FDA-approved and FDA does not review its safety, effectiveness or quality before marketing. Approved labeling does not establish equivalence of a compounded preparation. [12]

Read Somira’s compounding notice. Confirm ingredients, instructions and storage with your dispensing pharmacist.

Your prescription, storage & follow-up

Use only your prescribed product and instructions. Ask the pharmacist to clarify any confusing label before using it; do not copy another person’s schedule. For injections, obtain hands-on or provider-approved training and the correct supplies. Storage and discard instructions must match the product you receive.

Keep the care team informed about medicines, supplements, allergies and treatment problems. This guide is not a dosing calculator or permission to combine treatments.

Sources & full medication information

Sources checked September 17, 2026. Full labeling includes risks and instructions not reproduced here. Branded references do not mean those brands are supplied; the testosterone patient resource also discusses other testosterone formulations. Follow the instructions for your actual prescription.

  1. Somira: current Men’s Health treatments and plan availability (new tab)
  2. Viagra (sildenafil): official prescribing information (new tab)
  3. MedlinePlus: sildenafil patient information (new tab)
  4. Cialis (tadalafil): official prescribing information (PDF) (new tab)
  5. MedlinePlus: tadalafil patient information (new tab)
  6. Depo-Testosterone (testosterone cypionate): official labeling (new tab)
  7. Endocrine Society: testosterone therapy guideline (new tab)
  8. FDA: testosterone labeling and blood-pressure warnings (new tab)
  9. MedlinePlus: testosterone injection patient information (new tab)
  10. Pregnyl (HCG): official prescribing information (PDF) (new tab)
  11. FDA: HCG is not approved for weight loss (new tab)
  12. FDA: understanding compounded-drug risks (new tab)
  13. Pubmed: Treatment that maintains fertility in men with secondary hypogonadism (new tab)

Educational information for adults, not a diagnosis or personalized treatment advice. Prescription and provider approval required. This summary is not exhaustive and does not replace your medication labeling or clinician/pharmacist counseling.

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We believe patients deserve clear information, honest pricing, and the freedom to make informed decisions about their health without unnecessary barriers or hidden costs.

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